Electrochemical Trifluoromethylation of Isonicotinic acid hydrazide using Cyclic Voltammetry and Galvanostatic Electrolysis

Isonicotinic Acid Hydrazide

Oxidation of chlorophenols on Pt electrode in alkaline solution studied by cyclic voltammetry, galvanostatic electrolysis, and gas chromatography–mass spectrometry*

Potentiodynamic investigations on a platinum electrode show that oxidation of phenol, monochlorophenols, dichlorophenols, 2,3,6-, 2,4,5-, 2,4,6-trichlorophenols, and pentachlorophenol in 1 M NaOH solution, containing 1 mM of phenols, proceeds in the potential region of Pt oxide formation. The oxidation rate of phenols decreases with the increase in the number of chlorine atoms in the benzene ri...

Charge Transfer Interactions between Isonicotinic Acid Hydrazide and Cupric Ions

The interaction of Cu2+ with isonicotinic acid hydrazide (INH) and some of its derivatives has been investigated by means of electron spin resonance, nuclear magnetic resonance, and optical absorption studies. It could be shown that an interaction exists between the metal ions and the hydrazine side chain in addition to the very weak interaction with the ring nitrogen. The results obtained indi...

Isonicotinic Acid Hydrazide in the Treatment of Lupus Vulgaris

Isonicotinic acid hydrazide (rimifon) in the treatment of tuberculosis.

Following reports on the effectiveness of isonicotinic acid hydrazide in the treatment of tuberculosis,’ a clinical trial was instituted at the San Angel Sanatorium in Mexico City. Beginning in March 1952, a series of 13 hospitalized and 12 ambulatory patients were started on therapy with Rlmifon* and the results evaluated at the end of a 90-day period. The hospitalized patients selected for st...